Objective: Social Determinants of Health (SDOH) influence personal health outcomes and health systems interactions. Health systems capture SDOH information through structured data and unstructured clinical notes; however, clinical notes often contain a more comprehensive representation of several key SDOH. The objective of this work is to assess the SDOH information gain achievable by extracting structured semantic representations of SDOH from the clinical narrative and combining these extracted representations with available structured data. Materials and Methods: We developed a natural language processing (NLP) information extraction model for SDOH that utilizes a deep learning entity and relation extraction architecture. In an electronic health record (EHR) case study, we applied the SDOH extractor to a large existing clinical data set with over 200,000 patients and 400,000 notes and compared the extracted information with available structured data. Results: The SDOH extractor achieved 0.86 F1 on a withheld test set. In the EHR case study, we found 19\% of current tobacco users, 10\% of drug users, and 32\% of homeless patients only include documentation of these risk factors in the clinical narrative. Conclusions: Patients who are at-risk for negative health outcomes due to SDOH may be better served if health systems are able to identify SDOH risk factors and associated social needs. Structured semantic representations of text-encoded SDOH information can augment existing structured, and this more comprehensive SDOH representation can assist health systems in identifying and addressing social needs.

Multi-object state estimation is a fundamental problem for robotic applications where a robot must interact with other moving objects. Typically, other objects' relevant state features are not directly observable, and must instead be inferred from observations. Particle filtering can perform such inference given approximate transition and observation models. However, these models are often unknown a priori, yielding a difficult parameter estimation problem since observations jointly carry transition and observation noise. In this work, we consider learning maximum-likelihood parameters using particle methods. Recent methods addressing this problem typically differentiate through time in a particle filter, which requires workarounds to the non-differentiable resampling step, that yield biased or high variance gradient estimates. By contrast, we exploit Fisher's identity to obtain a particle-based approximation of the score function (the gradient of the log likelihood) that yields a low variance estimate while only requiring stepwise differentiation through the transition and observation models. We apply our method to real data collected from autonomous vehicles (AVs) and show that it learns better models than existing techniques and is more stable in training, yielding an effective smoother for tracking the trajectories of vehicles around an AV.

脑肿瘤分割是医学图像处理中的重要任务。早期诊断脑肿瘤在改善治疗可能性方面发挥着至关重要的作用，并提高了患者的存活率。手动分割癌症诊断的脑肿瘤，从大量MRI图像中，都是难以耗时的任务。需要自动脑肿瘤图像分割。该项目的目的是提供MRI图像的自动脑肿瘤分割方法，以帮助准确且快速地定位肿瘤。

We introduce Argoverse 2 (AV2) - a collection of three datasets for perception and forecasting research in the self-driving domain. The annotated Sensor Dataset contains 1,000 sequences of multimodal data, encompassing high-resolution imagery from seven ring cameras, and two stereo cameras in addition to lidar point clouds, and 6-DOF map-aligned pose. Sequences contain 3D cuboid annotations for 26 object categories, all of which are sufficiently-sampled to support training and evaluation of 3D perception models. The Lidar Dataset contains 20,000 sequences of unlabeled lidar point clouds and map-aligned pose. This dataset is the largest ever collection of lidar sensor data and supports self-supervised learning and the emerging task of point cloud forecasting. Finally, the Motion Forecasting Dataset contains 250,000 scenarios mined for interesting and challenging interactions between the autonomous vehicle and other actors in each local scene. Models are tasked with the prediction of future motion for "scored actors" in each scenario and are provided with track histories that capture object location, heading, velocity, and category. In all three datasets, each scenario contains its own HD Map with 3D lane and crosswalk geometry - sourced from data captured in six distinct cities. We believe these datasets will support new and existing machine learning research problems in ways that existing datasets do not. All datasets are released under the CC BY-NC-SA 4.0 license.

Object movement identification is one of the most researched problems in the field of computer vision. In this task, we try to classify a pixel as foreground or background. Even though numerous traditional machine learning and deep learning methods already exist for this problem, the two major issues with most of them are the need for large amounts of ground truth data and their inferior performance on unseen videos. Since every pixel of every frame has to be labeled, acquiring large amounts of data for these techniques gets rather expensive. Recently, Zhao et al. [1] proposed one of a kind Arithmetic Distribution Neural Network (ADNN) for universal background subtraction which utilizes probability information from the histogram of temporal pixels and achieves promising results. Building onto this work, we developed an intelligent video surveillance system that uses ADNN architecture for motion detection, trims the video with parts only containing motion, and performs anomaly detection on the trimmed video.

The machine translation mechanism translates texts automatically between different natural languages, and Neural Machine Translation (NMT) has gained attention for its rational context analysis and fluent translation accuracy. However, processing low-resource languages that lack relevant training attributes like supervised data is a current challenge for Natural Language Processing (NLP). We incorporated a technique known Active Learning with the NMT toolkit Joey NMT to reach sufficient accuracy and robust predictions of low-resource language translation. With active learning, a semi-supervised machine learning strategy, the training algorithm determines which unlabeled data would be the most beneficial for obtaining labels using selected query techniques. We implemented two model-driven acquisition functions for selecting the samples to be validated. This work uses transformer-based NMT systems; baseline model (BM), fully trained model (FTM) , active learning least confidence based model (ALLCM), and active learning margin sampling based model (ALMSM) when translating English to Hindi. The Bilingual Evaluation Understudy (BLEU) metric has been used to evaluate system results. The BLEU scores of BM, FTM, ALLCM and ALMSM systems are 16.26, 22.56 , 24.54, and 24.20, respectively. The findings in this paper demonstrate that active learning techniques helps the model to converge early and improve the overall quality of the translation system.

We study the problem of planning under model uncertainty in an online meta-reinforcement learning (RL) setting where an agent is presented with a sequence of related tasks with limited interactions per task. The agent can use its experience in each task and across tasks to estimate both the transition model and the distribution over tasks. We propose an algorithm to meta-learn the underlying structure across tasks, utilize it to plan in each task, and upper-bound the regret of the planning loss. Our bound suggests that the average regret over tasks decreases as the number of tasks increases and as the tasks are more similar. In the classical single-task setting, it is known that the planning horizon should depend on the estimated model's accuracy, that is, on the number of samples within task. We generalize this finding to meta-RL and study this dependence of planning horizons on the number of tasks. Based on our theoretical findings, we derive heuristics for selecting slowly increasing discount factors, and we validate its significance empirically.

As language models have grown in parameters and layers, it has become much harder to train and infer with them on single GPUs. This is severely restricting the availability of large language models such as GPT-3, BERT-Large, and many others. A common technique to solve this problem is pruning the network architecture by removing transformer heads, fully-connected weights, and other modules. The main challenge is to discern the important parameters from the less important ones. Our goal is to find strong metrics for identifying such parameters. We thus propose two strategies: Cam-Cut based on the GradCAM interpretations, and Smooth-Cut based on the SmoothGrad, for calculating the importance scores. Through this work, we show that our scoring functions are able to assign more relevant task-based scores to the network parameters, and thus both our pruning approaches significantly outperform the standard weight and gradient-based strategies, especially at higher compression ratios in BERT-based models. We also analyze our pruning masks and find them to be significantly different from the ones obtained using standard metrics.

Neoplasms (NPs) and neurological diseases and disorders (NDDs) are amongst the major classes of diseases underlying deaths of a disproportionate number of people worldwide. To determine if there exist some distinctive features in the local wiring patterns of protein interactions emerging at the onset of a disease belonging to either of these two classes, we examined 112 and 175 protein interaction networks belonging to NPs and NDDs, respectively. Orbit usage profiles (OUPs) for each of these networks were enumerated by investigating the networks' local topology. 56 non-redundant OUPs (nrOUPs) were derived and used as network features for classification between these two disease classes. Four machine learning classifiers, namely, k-nearest neighbour (KNN), support vector machine (SVM), deep neural network (DNN), random forest (RF) were trained on these data. DNN obtained the greatest average AUPRC (0.988) among these classifiers. DNNs developed on node2vec and the proposed nrOUPs embeddings were compared using 5-fold cross validation on the basis of average values of the six of performance measures, viz., AUPRC, Accuracy, Sensitivity, Specificity, Precision and MCC. It was found that nrOUPs based classifier performed better in all of these six performance measures.

Customers are rapidly turning to social media for customer support. While brand agents on these platforms are motivated and well-intentioned to help and engage with customers, their efforts are often ignored if their initial response to the customer does not match a specific tone, style, or topic the customer is aiming to receive. The length of a conversation can reflect the effort and quality of the initial response made by a brand toward collaborating and helping consumers, even when the overall sentiment of the conversation might not be very positive. Thus, through this study, we aim to bridge this critical gap in the existing literature by analyzing language's content and stylistic aspects such as expressed empathy, psycho-linguistic features, dialogue tags, and metrics for quantifying personalization of the utterances that can influence the engagement of an interaction. This paper demonstrates that we can predict engagement using initial customer and brand posts.